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Discussion Recently, a novel bifunctional enzyme GshF has aroused concerns about GSH productive capacity as most reported GshFs are insensitive to feedback inhibition of GSH except that of P

Acknowledgements We acknowledge Cure Parkinsons UK Grant CP: SC01 and Fundao para a Cincia e a Tecnologia, through projects IN1458_GAinPD_COMPETE2030-FEDER-00675300, UIDB/04539/2020, UIDP/04539/2020, and LA/P/0058/2020, awarded to the Centre for Innovative Biomedicine and Biotechnology, for advancing our research in the field of Parkinsons Disease and biomedicine